All the World's a Stage: Facilitating Discovery Science and Improved Cancer Care through the Global Alliance for Genomics and Health.
Identifieur interne : 003194 ( Main/Exploration ); précédent : 003193; suivant : 003195All the World's a Stage: Facilitating Discovery Science and Improved Cancer Care through the Global Alliance for Genomics and Health.
Auteurs : Mark Lawler [Royaume-Uni] ; Lillian L. Siu [Canada] ; Heidi L. Rehm [États-Unis] ; Stephen J. Chanock [États-Unis] ; Gil Alterovitz [États-Unis] ; John Burn [Royaume-Uni] ; Fabien Calvo [France] ; Denis Lacombe [Belgique] ; Bin Tean Teh [Singapour] ; Kathryn N. North [Australie] ; Charles L. Sawyers [États-Unis]Source :
- Cancer discovery [ 2159-8290 ] ; 2015.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
Abstract
The recent explosion of genetic and clinical data generated from tumor genome analysis presents an unparalleled opportunity to enhance our understanding of cancer, but this opportunity is compromised by the reluctance of many in the scientific community to share datasets and the lack of interoperability between different data platforms. The Global Alliance for Genomics and Health is addressing these barriers and challenges through a cooperative framework that encourages "team science" and responsible data sharing, complemented by the development of a series of application program interfaces that link different data platforms, thus breaking down traditional silos and liberating the data to enable new discoveries and ultimately benefit patients.
DOI: 10.1158/2159-8290.CD-15-0821
PubMed: 26526696
Affiliations:
- Australie, Belgique, Canada, France, Royaume-Uni, Singapour, États-Unis
- District de Columbia, Massachusetts, Région de Bruxelles-Capitale, Victoria (État), État de New York
- Bruxelles, Melbourne
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Le document en format XML
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Siu</name><affiliation wicri:level="1"><nlm:affiliation>University Health Network, Toronto, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>University Health Network, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Rehm, Heidi L" sort="Rehm, Heidi L" uniqKey="Rehm H" first="Heidi L" last="Rehm">Heidi L. Rehm</name><affiliation wicri:level="2"><nlm:affiliation>Harvard Medical School, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Harvard Medical School, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J" last="Chanock">Stephen J. Chanock</name><affiliation wicri:level="2"><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Washington, DC.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">District de Columbia</region></placeName><wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Washington</wicri:cityArea></affiliation></author><author><name sortKey="Alterovitz, Gil" sort="Alterovitz, Gil" uniqKey="Alterovitz G" first="Gil" last="Alterovitz">Gil Alterovitz</name><affiliation wicri:level="2"><nlm:affiliation>Harvard Medical School, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Harvard Medical School, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Burn, John" sort="Burn, John" uniqKey="Burn J" first="John" last="Burn">John Burn</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne</wicri:regionArea><wicri:noRegion>Newcastle upon Tyne</wicri:noRegion></affiliation></author><author><name sortKey="Calvo, Fabien" sort="Calvo, Fabien" uniqKey="Calvo F" first="Fabien" last="Calvo">Fabien Calvo</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Core Europe and Institute Gustave Roussy Cancer Campus, Grand Paris, Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Cancer Core Europe and Institute Gustave Roussy Cancer Campus, Grand Paris, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Lacombe, Denis" sort="Lacombe, Denis" uniqKey="Lacombe D" first="Denis" last="Lacombe">Denis Lacombe</name><affiliation wicri:level="3"><nlm:affiliation>European Organisation for the Research and Treatment of Cancer, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>European Organisation for the Research and Treatment of Cancer, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Teh, Bin Tean" sort="Teh, Bin Tean" uniqKey="Teh B" first="Bin Tean" last="Teh">Bin Tean Teh</name><affiliation wicri:level="1"><nlm:affiliation>National Cancer Centre Singapore, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>National Cancer Centre Singapore</wicri:regionArea></affiliation></author><author><name sortKey="North, Kathryn N" sort="North, Kathryn N" uniqKey="North K" first="Kathryn N" last="North">Kathryn N. North</name><affiliation wicri:level="3"><nlm:affiliation>Murdoch Children's Research Institute, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Murdoch Children's Research Institute, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Sawyers, Charles L" sort="Sawyers, Charles L" uniqKey="Sawyers C" first="Charles L" last="Sawyers">Charles L. Sawyers</name><affiliation wicri:level="2"><nlm:affiliation>Memorial Sloan Kettering Cancer Center, New York, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Memorial Sloan Kettering Cancer Center, New York</wicri:cityArea></affiliation></author></analytic><series><title level="j">Cancer discovery</title><idno type="eISSN">2159-8290</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cooperative Behavior</term><term>Databases, Genetic</term><term>Drug Discovery (methods)</term><term>Genomics (methods)</term><term>Global Health</term><term>Humans</term><term>Information Dissemination</term><term>Medical Oncology</term><term>Precision Medicine (methods)</term><term>Research</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Bases de données génétiques</term><term>Comportement coopératif</term><term>Diffusion de l'information</term><term>Découverte de médicament ()</term><term>Génomique ()</term><term>Humains</term><term>Médecine individualisée ()</term><term>Oncologie médicale</term><term>Recherche</term><term>Santé mondiale</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Drug Discovery</term><term>Genomics</term><term>Precision Medicine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Cooperative Behavior</term><term>Databases, Genetic</term><term>Global Health</term><term>Humans</term><term>Information Dissemination</term><term>Medical Oncology</term><term>Research</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Bases de données génétiques</term><term>Comportement coopératif</term><term>Diffusion de l'information</term><term>Découverte de médicament</term><term>Génomique</term><term>Humains</term><term>Médecine individualisée</term><term>Oncologie médicale</term><term>Recherche</term><term>Santé mondiale</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The recent explosion of genetic and clinical data generated from tumor genome analysis presents an unparalleled opportunity to enhance our understanding of cancer, but this opportunity is compromised by the reluctance of many in the scientific community to share datasets and the lack of interoperability between different data platforms. The Global Alliance for Genomics and Health is addressing these barriers and challenges through a cooperative framework that encourages "team science" and responsible data sharing, complemented by the development of a series of application program interfaces that link different data platforms, thus breaking down traditional silos and liberating the data to enable new discoveries and ultimately benefit patients.</div></front></TEI><affiliations><list><country><li>Australie</li><li>Belgique</li><li>Canada</li><li>France</li><li>Royaume-Uni</li><li>Singapour</li><li>États-Unis</li></country><region><li>District de Columbia</li><li>Massachusetts</li><li>Région de Bruxelles-Capitale</li><li>Victoria (État)</li><li>État de New York</li></region><settlement><li>Bruxelles</li><li>Melbourne</li></settlement></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Lawler, Mark" sort="Lawler, Mark" uniqKey="Lawler M" first="Mark" last="Lawler">Mark Lawler</name></noRegion><name sortKey="Burn, John" sort="Burn, John" uniqKey="Burn J" first="John" last="Burn">John Burn</name></country><country name="Canada"><noRegion><name sortKey="Siu, Lillian L" sort="Siu, Lillian L" uniqKey="Siu L" first="Lillian L" last="Siu">Lillian L. Siu</name></noRegion></country><country name="États-Unis"><region name="Massachusetts"><name sortKey="Rehm, Heidi L" sort="Rehm, Heidi L" uniqKey="Rehm H" first="Heidi L" last="Rehm">Heidi L. Rehm</name></region><name sortKey="Alterovitz, Gil" sort="Alterovitz, Gil" uniqKey="Alterovitz G" first="Gil" last="Alterovitz">Gil Alterovitz</name><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J" last="Chanock">Stephen J. Chanock</name><name sortKey="Sawyers, Charles L" sort="Sawyers, Charles L" uniqKey="Sawyers C" first="Charles L" last="Sawyers">Charles L. Sawyers</name></country><country name="France"><noRegion><name sortKey="Calvo, Fabien" sort="Calvo, Fabien" uniqKey="Calvo F" first="Fabien" last="Calvo">Fabien Calvo</name></noRegion></country><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Lacombe, Denis" sort="Lacombe, Denis" uniqKey="Lacombe D" first="Denis" last="Lacombe">Denis Lacombe</name></region></country><country name="Singapour"><noRegion><name sortKey="Teh, Bin Tean" sort="Teh, Bin Tean" uniqKey="Teh B" first="Bin Tean" last="Teh">Bin Tean Teh</name></noRegion></country><country name="Australie"><region name="Victoria (État)"><name sortKey="North, Kathryn N" sort="North, Kathryn N" uniqKey="North K" first="Kathryn N" last="North">Kathryn N. North</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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